Born in London to Greek parents, Sirtis attended the Guild Hall School of Music and Drama. After graduating, she became a member of the Worthing Repertory Theater, where she made her debut as Ophelia in “Hamlet.” She went on to appear in the productions of several European theatrical companies, including Coventry Rep's The Hunchback of Notre Dame (in the role of Esmeralda) and in The Rocky Horror Picture Show (as Magenta). Sirtis worked extensively in British television, but won roles in several American films, including The Wicked Lady with Faye Dunaway, Death Wish III opposite Charles Bronson, and Blind Date with Bruce Willis. Hoping to find more work in the U.S., she moved to Los Angeles in 1986, winning a role in Star Trek: The Next Generation the following year. Her last appearance as Deanna Troi was, ironically, in an episode of Star Trek: Enterprise, where she played opposite her longtime co-star Jonathan Frakes. In recent years, she has played a recurring role in the syndicated comedy Girlfriends and guest-starred on Without a Trace and Three Rivers.