- Star Trek: The Motion Picture
- Star Trek II: The Wrath of Khan
- Star Trek III: The Search for Spock
- Star Trek IV: The Voyage Home
- Star Trek V: The Final Frontier
- Star Trek VI: The Undiscovered Country
- Star Trek Generations
In an alternate timeline, influenced by Q and created via a spatial anomaly in the Neutral Zone, this version of the Enterprise-D came to the Pasteur's aid when that ship was under attack by a future design of Klingon vessel.
This Enterprise featured advanced weaponry and a third warp nacelle, which allowed the ship to travel at a double-digit warp speed.