Initially commissioned circa 2245, this type of Federation starship is one of the most well-known. The original U.S.S. Enterprise NCC-1701 is of this class.

Others have included the U.S.S. Excalibur, NCC-1664, the U.S.S. Exeter, NCC-1672 and the U.S.S. Potemkin, NCC-1657.