- Star Trek: The Motion Picture
- Star Trek II: The Wrath of Khan
- Star Trek III: The Search for Spock
- Star Trek IV: The Voyage Home
- Star Trek V: The Final Frontier
- Star Trek VI: The Undiscovered Country
- Star Trek Generations
A Federation starship among those destroyed in the Battle of Wolf 359 with the Borg, as Commander Sisko recalled the incident on stardate 46379.1. The ship is named for the mythical Greek hero who slew the Chimera with the aid of Pegasus.